Cargando…

Extensive longitudinal immune profiling reveals sustained innate immune activaton in COVID-19 patients with unfavorable outcome

COVID-19 differs substantially between individuals, ranging from mild to severe or even fatal. Heterogeneity in the immune response against SARS-COV-2 likely contributes to this. Therefore, we explored the temporal dynamics of key cellular and soluble mediators of innate and adaptive immune activati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schrijver, Benjamin, Assmann, Jorn L. J. C., van Gammeren, Adriaan J., Vermeulen, Roel C. H., Portengen, Lützen, Heukels, Peter, Langerak, Anton W., Dik, Willem A., van der Velden, Vincent H. J., Ermens, Ton A. A. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Libbey Eurotext 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937051/ https://www.ncbi.nlm.nih.gov/pubmed/33648924 http://dx.doi.org/10.1684/ecn.2020.0456

Ejemplares similares

Severe COVID-19 Is Characterised by Perturbations in Plasma Amines Correlated with Immune Response Markers, and Linked to Inflammation and Oxidative Stress
por: Karu, Naama, et al.
Publicado: (2022)

Plasma Oxylipins and Their Precursors Are Strongly Associated with COVID-19 Severity and with Immune Response Markers
por: Karu, Naama, et al.
Publicado: (2022)

TRB sequences targeting ORF1a/b are associated with disease severity in hospitalized COVID‐19 patients
por: Assmann, Jorn L.J.C., et al.
Publicado: (2021)

Antibodies Against Angiotensin II Receptor Type 1 and Endothelin A Receptor Are Associated With an Unfavorable COVID19 Disease Course
por: Miedema, Jelle, et al.
Publicado: (2021)

Aplastic bone marrow with Cabot rings in blood due to high‐dose olmesartan
por: Joosen, Annemiek M.C.P., et al.
Publicado: (2022)

Meta-Analysis of Lung Cancer Risk from Exposure to Diesel Exhaust: Vermeulen et al. Respond
por: Vermeulen, Roel, et al.
Publicado: (2014)

Metal Exposure and Risk of Parkinson Disease: A Systematic Review and Meta-Analysis
por: Zhao, Yujia, et al.
Publicado: (2023)

Flexible Meta-Regression to Assess the Shape of the Benzene–Leukemia Exposure–Response Curve
por: Vlaanderen, Jelle, et al.
Publicado: (2010)

Exposure-Response Estimates for Diesel Engine Exhaust and Lung Cancer Mortality Based on Data from Three Occupational Cohorts
por: Vermeulen, Roel, et al.
Publicado: (2013)

Plasma Cytokine Concentrations in Workers Exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
por: Saberi Hosnijeh, Fatemeh, et al.
Publicado: (2012)

A Meta-analysis of Asbestos and Lung Cancer: Is Better Quality Exposure Assessment Associated with Steeper Slopes of the Exposure–Response Relationships?
por: Lenters, Virissa, et al.
Publicado: (2011)

Prenatal Exposure to Metabolism-Disrupting Chemicals, Cord Blood Transcriptome Perturbations, and Birth Weight in a Belgian Birth Cohort
por: Cai, Anran, et al.
Publicado: (2023)

The impact of alternative historical extrapolations of diesel exhaust exposure and radon in the Diesel Exhaust in Miners Study (DEMS)
por: Vermeulen, Roel, et al.
Publicado: (2020)

A Multipollutant Approach to Estimating Causal Effects of Air Pollution Mixtures on Overall Mortality in a Large, Prospective Cohort
por: Traini, Eugenio, et al.
Publicado: (2022)

The Authors Respond
por: Traini, Eugenio, et al.
Publicado: (2022)

The Diesel Exhaust in Miners Study: IV. Estimating Historical Exposures to Diesel Exhaust in Underground Non-metal Mining Facilities
por: Vermeulen, Roel, et al.
Publicado: (2010)

A Quantitative Meta-Analysis of the Relation between Occupational Benzene Exposure and Biomarkers of Cytogenetic Damage
por: Scholten, Bernice, et al.
Publicado: (2020)

Clinical Outcomes of Patients With Metastatic NSCLC After Discontinuation of Immunotherapy Because of Immune-Related Adverse Effects
por: Lievense, Lysanne A., et al.
Publicado: (2022)

Polycyclic Aromatic Hydrocarbon Exposure in Household Air Pollution from Solid Fuel Combustion among the Female Population of Xuanwei and Fuyuan Counties, China
por: Downward, George S., et al.
Publicado: (2014)

Prenatal Phthalate, Perfluoroalkyl Acid, and Organochlorine Exposures and Term Birth Weight in Three Birth Cohorts: Multi-Pollutant Models Based on Elastic Net Regression
por: Lenters, Virissa, et al.
Publicado: (2015)

Exploratory analysis of interleukin‐38 in hospitalized COVID‐19 patients
por: de Graaf, Dennis M., et al.
Publicado: (2022)

Multiple segmental and selective isotope labeling of large RNA for NMR structural studies
por: Nelissen, Frank H. T., et al.
Publicado: (2008)

Loss of immune homeostasis in patients with idiopathic pulmonary arterial hypertension
por: Heukels, Peter, et al.
Publicado: (2021)

Endotoxin exposure and lung cancer risk: a systematic review and meta-analysis of the published literature on agriculture and cotton textile workers
por: Lenters, Virissa, et al.
Publicado: (2009)

Inflammatory T-lymphocyte proliferation in morbid obesity
por: Van der Weerd, K, et al.
Publicado: (2010)

Exploring the nature of prediagnostic blood transcriptome markers of chronic lymphocytic leukemia by assessing their overlap with the transcriptome at the clinical stage
por: Vlaanderen, Jelle, et al.
Publicado: (2017)

DCK is an Unfavorable Prognostic Biomarker and Correlated With Immune Infiltrates in Liver Cancer
por: Hu, Shu Fang, et al.
Publicado: (2020)

Immunity of international organizations
por: Blokker, Niels, et al.
Publicado: (2015)

Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma
por: Mitra, Akash, et al.
Publicado: (2020)

FN1 overexpression is correlated with unfavorable prognosis and immune infiltrates in breast cancer
por: Zhang, Xiu-Xia, et al.
Publicado: (2022)

Immune‐related lncRNA signature delineates an immune‐excluded subtype of liver cancer with unfavorable clinical outcomes
por: Chen, Yawei, et al.
Publicado: (2022)

Exposure to soluble platinum salts in precious metal refinery workers over a 17-year period
por: Smit, Lidwien A M, et al.
Publicado: (2023)

Quantifying topical antimicrobial use before and during participation in an antimicrobial stewardship programme in Dutch companion animal clinics
por: Kardomatea, Nafsika, et al.
Publicado: (2023)

Adipogenesis in triple-negative breast cancer is associated with unfavorable tumor immune microenvironment and with worse survival
por: Oshi, Masanori, et al.
Publicado: (2021)

Differential Expression of DNA Repair Genes in Prognostically-Favorable versus Unfavorable Uveal Melanoma
por: Dogrusöz, Mehmet, et al.
Publicado: (2019)

Prediagnostic Serum Organochlorine Concentrations and Metastatic Prostate Cancer: A Nested Case–Control Study in the Norwegian Janus Serum Bank Cohort
por: Koutros, Stella, et al.
Publicado: (2015)

A Systematic Comparison of Linear Regression–Based Statistical Methods to Assess Exposome-Health Associations
por: Agier, Lydiane, et al.
Publicado: (2016)

Modulation of Human Immune Responses by Bovine Interleukin-10
por: den Hartog, Gerco, et al.
Publicado: (2011)

Morbidly Obese Human Subjects Have Increased Peripheral Blood CD4(+) T Cells With Skewing Toward a Treg- and Th2-Dominated Phenotype
por: van der Weerd, Kim, et al.
Publicado: (2012)

High systemic immune–inflammation index represents an unfavorable prognosis of malignant pleural mesothelioma
por: Ma, Ming, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_6cmii65oueg57gh2hgklmkkjdm