Targeting Bruton tyrosine kinase using non-covalent inhibitors in B cell malignancies

B cell receptor (BCR) signaling is involved in the pathogenesis of B cell malignancies. Activation of BCR signaling promotes the survival and proliferation of malignant B cells. Bruton tyrosine kinase (BTK) is a key component of BCR signaling, establishing BTK as an important therapeutic target. Sev...

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Detalles Bibliográficos
Autores principales: Gu, Danling, Tang, Hanning, Wu, Jiazhu, Li, Jianyong, Miao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937220/
https://www.ncbi.nlm.nih.gov/pubmed/33676527
http://dx.doi.org/10.1186/s13045-021-01049-7

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