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Sex differences in noise-induced hearing loss: a cross-sectional study in China
BACKGROUND: Significant sex differences exist in hearing physiology, while few human studies have investigated sex differences in noise-induced hearing loss (NIHL), and the sex bias in previous studies resulted in inadequate female data. The study aims to investigate sex differences in the character...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937304/ https://www.ncbi.nlm.nih.gov/pubmed/33676563 http://dx.doi.org/10.1186/s13293-021-00369-0 |
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author | Wang, Qixuan Wang, Xueling Yang, Lu Han, Kun Huang, Zhiwu Wu, Hao |
author_facet | Wang, Qixuan Wang, Xueling Yang, Lu Han, Kun Huang, Zhiwu Wu, Hao |
author_sort | Wang, Qixuan |
collection | PubMed |
description | BACKGROUND: Significant sex differences exist in hearing physiology, while few human studies have investigated sex differences in noise-induced hearing loss (NIHL), and the sex bias in previous studies resulted in inadequate female data. The study aims to investigate sex differences in the characteristics of NIHL to provide insight into sex-specific risk factors, prevention strategies and treatment for NIHL. METHODS: This cross-sectional study included 2280 industrial noise-exposed shipyard workers (1140 males and 1140 females matched for age, job and employment length) in China. Individual noise exposure levels were measured to calculate the cumulative noise exposure (CNE), and an audiometric test was performed by an experienced technician in a soundproof booth. Sex differences in and influencing factors of low-frequency (LFHL) and high-frequency hearing loss (HFHL) were analyzed using logistic regression models stratified by age and CNE. RESULTS: At comparable noise exposure levels and ages, the prevalence of HFHL was significantly higher in males (34.4%) than in females (13.8%), and males had a higher prevalence of HFHL (OR = 4.19, 95% CI 3.18 to 5.52) after adjusting for age, CNE, and other covariates. Sex differences were constant and highly remarkable among subjects aged 30 to 40 years and those with a CNE of 80 to 95 dB(A). Alcohol consumption might be a risk factor for HFHL in females (OR = 3.12, 95% CI 1.10 to 8.89). CONCLUSIONS: This study indicates significant sex differences in NIHL. Males are at higher risk of HFHL than females despite equivalent noise exposure and age. The risk factors for NIHL might be different in males and females. |
format | Online Article Text |
id | pubmed-7937304 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-79373042021-03-09 Sex differences in noise-induced hearing loss: a cross-sectional study in China Wang, Qixuan Wang, Xueling Yang, Lu Han, Kun Huang, Zhiwu Wu, Hao Biol Sex Differ Research BACKGROUND: Significant sex differences exist in hearing physiology, while few human studies have investigated sex differences in noise-induced hearing loss (NIHL), and the sex bias in previous studies resulted in inadequate female data. The study aims to investigate sex differences in the characteristics of NIHL to provide insight into sex-specific risk factors, prevention strategies and treatment for NIHL. METHODS: This cross-sectional study included 2280 industrial noise-exposed shipyard workers (1140 males and 1140 females matched for age, job and employment length) in China. Individual noise exposure levels were measured to calculate the cumulative noise exposure (CNE), and an audiometric test was performed by an experienced technician in a soundproof booth. Sex differences in and influencing factors of low-frequency (LFHL) and high-frequency hearing loss (HFHL) were analyzed using logistic regression models stratified by age and CNE. RESULTS: At comparable noise exposure levels and ages, the prevalence of HFHL was significantly higher in males (34.4%) than in females (13.8%), and males had a higher prevalence of HFHL (OR = 4.19, 95% CI 3.18 to 5.52) after adjusting for age, CNE, and other covariates. Sex differences were constant and highly remarkable among subjects aged 30 to 40 years and those with a CNE of 80 to 95 dB(A). Alcohol consumption might be a risk factor for HFHL in females (OR = 3.12, 95% CI 1.10 to 8.89). CONCLUSIONS: This study indicates significant sex differences in NIHL. Males are at higher risk of HFHL than females despite equivalent noise exposure and age. The risk factors for NIHL might be different in males and females. BioMed Central 2021-03-06 /pmc/articles/PMC7937304/ /pubmed/33676563 http://dx.doi.org/10.1186/s13293-021-00369-0 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Wang, Qixuan Wang, Xueling Yang, Lu Han, Kun Huang, Zhiwu Wu, Hao Sex differences in noise-induced hearing loss: a cross-sectional study in China |
title | Sex differences in noise-induced hearing loss: a cross-sectional study in China |
title_full | Sex differences in noise-induced hearing loss: a cross-sectional study in China |
title_fullStr | Sex differences in noise-induced hearing loss: a cross-sectional study in China |
title_full_unstemmed | Sex differences in noise-induced hearing loss: a cross-sectional study in China |
title_short | Sex differences in noise-induced hearing loss: a cross-sectional study in China |
title_sort | sex differences in noise-induced hearing loss: a cross-sectional study in china |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937304/ https://www.ncbi.nlm.nih.gov/pubmed/33676563 http://dx.doi.org/10.1186/s13293-021-00369-0 |
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