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Gastric Perforation Secondary to Fungal Gastritis in an Immuno-Competent Adult

Gastrointestinal (GI) tract perforation is a surgical emergency. The epidemiology and etiology of perforation vary considerably across geography. Lower GI tract perforations in the elderly predominate in the West compared to upper GI perforations in the younger population in the tropics. Fungi and v...

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Detalles Bibliográficos
Autores principales: Rai, Ankit, Gajula, Bhargav, Kumar, Navin, Malik, Akanksha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937405/
https://www.ncbi.nlm.nih.gov/pubmed/33692925
http://dx.doi.org/10.7759/cureus.13156
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author Rai, Ankit
Gajula, Bhargav
Kumar, Navin
Malik, Akanksha
author_facet Rai, Ankit
Gajula, Bhargav
Kumar, Navin
Malik, Akanksha
author_sort Rai, Ankit
collection PubMed
description Gastrointestinal (GI) tract perforation is a surgical emergency. The epidemiology and etiology of perforation vary considerably across geography. Lower GI tract perforations in the elderly predominate in the West compared to upper GI perforations in the younger population in the tropics. Fungi and viruses have been reported to cause GI perforations in immuno-compromised individuals but it is rare in immuno-competent individuals. We report a very rare case of gastric perforation secondary to fungal gastritis in an immuno-competent 35-year-old female who presented with features of peritonitis. At emergency laparotomy, gastric perforation was found which was repaired by the Cellan-Jones method. Perforation edge biopsy findings were consistent with fungal etiology. She responded well to Antifungal therapy. We conclude that fungal etiology can be considered in patients with gastric perforation without any history of peptic ulcer disease (PUD) or use of oral non-steroidal anti-inflammatory drugs.
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spelling pubmed-79374052021-03-09 Gastric Perforation Secondary to Fungal Gastritis in an Immuno-Competent Adult Rai, Ankit Gajula, Bhargav Kumar, Navin Malik, Akanksha Cureus Emergency Medicine Gastrointestinal (GI) tract perforation is a surgical emergency. The epidemiology and etiology of perforation vary considerably across geography. Lower GI tract perforations in the elderly predominate in the West compared to upper GI perforations in the younger population in the tropics. Fungi and viruses have been reported to cause GI perforations in immuno-compromised individuals but it is rare in immuno-competent individuals. We report a very rare case of gastric perforation secondary to fungal gastritis in an immuno-competent 35-year-old female who presented with features of peritonitis. At emergency laparotomy, gastric perforation was found which was repaired by the Cellan-Jones method. Perforation edge biopsy findings were consistent with fungal etiology. She responded well to Antifungal therapy. We conclude that fungal etiology can be considered in patients with gastric perforation without any history of peptic ulcer disease (PUD) or use of oral non-steroidal anti-inflammatory drugs. Cureus 2021-02-05 /pmc/articles/PMC7937405/ /pubmed/33692925 http://dx.doi.org/10.7759/cureus.13156 Text en Copyright © 2021, Rai et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Emergency Medicine
Rai, Ankit
Gajula, Bhargav
Kumar, Navin
Malik, Akanksha
Gastric Perforation Secondary to Fungal Gastritis in an Immuno-Competent Adult
title Gastric Perforation Secondary to Fungal Gastritis in an Immuno-Competent Adult
title_full Gastric Perforation Secondary to Fungal Gastritis in an Immuno-Competent Adult
title_fullStr Gastric Perforation Secondary to Fungal Gastritis in an Immuno-Competent Adult
title_full_unstemmed Gastric Perforation Secondary to Fungal Gastritis in an Immuno-Competent Adult
title_short Gastric Perforation Secondary to Fungal Gastritis in an Immuno-Competent Adult
title_sort gastric perforation secondary to fungal gastritis in an immuno-competent adult
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937405/
https://www.ncbi.nlm.nih.gov/pubmed/33692925
http://dx.doi.org/10.7759/cureus.13156
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