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Antibodies to neutralising epitopes synergistically block the interaction of the receptor‐binding domain of SARS‐CoV‐2 to ACE 2
OBJECTIVES: A major COVID‐19 vaccine strategy is to induce antibodies that prevent interaction between the Spike protein's receptor‐binding domain (RBD) and angiotensin‐converting enzyme 2 (ACE2). These vaccines will also induce T‐cell responses. However, concerns were raised that aberrant vacc...
Autores principales: | Pandey, Manisha, Ozberk, Victoria, Eskandari, Sharareh, Shalash, Ahmed O, Joyce, Michael A, Saffran, Holly A, Day, Christopher J, Lepletier, Ailin, Spillings, Belinda L, Mills, Jamie‐Lee, Calcutt, Ainslie, Fan, Fan, Williams, James T, Stanisic, Danielle I, Hattingh, Laetitia, Gerrard, John, Skwarczynski, Mariusz, Mak, Johnson, Jennings, Michael P, Toth, Istvan, Tyrrell, D Lorne, Good, Michael F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937407/ https://www.ncbi.nlm.nih.gov/pubmed/33732459 http://dx.doi.org/10.1002/cti2.1260 |
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