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SIRT1 Inhibits Apoptosis by Promoting Autophagic Flux in Human Nucleus Pulposus Cells in the Key Stage of Degeneration via ERK Signal Pathway

BACKGROUND: The application of biomolecular interventions in the early stage of intervertebral disc degeneration (IVDD) is considered an ideal method for the treatment of IVDD. However, the precise definition of the “early stage” of IVDD is unclear. Silent information regulation 2 homologue-1 (SIRT1...

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Detalles Bibliográficos
Autores principales:	He, Fei, Li, Qingshu, Sheng, Bo, Yang, Haitao, Jiang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937464/ https://www.ncbi.nlm.nih.gov/pubmed/33728342 http://dx.doi.org/10.1155/2021/8818713

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