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Divergent trajectories of cellular bioenergetics, intermediary metabolism and systemic redox status in survivors and non-survivors of critical illness

BACKGROUND: Numerous pathologies result in multiple-organ failure, which is thought to be a direct consequence of compromised cellular bioenergetic status. Neither the nature of this phenotype nor its relevance to survival are well understood, limiting the efficacy of modern life-support. METHODS: T...

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Detalles Bibliográficos
Autores principales: McKenna, Helen T., O'Brien, Katie A., Fernandez, Bernadette O., Minnion, Magdalena, Tod, Adam, McNally, Ben D., West, James A., Griffin, Julian L., Grocott, Michael P., Mythen, Michael G., Feelisch, Martin, Murray, Andrew J., Martin, Daniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937570/
https://www.ncbi.nlm.nih.gov/pubmed/33667994
http://dx.doi.org/10.1016/j.redox.2021.101907