Mitogen-Inducible Gene 6 Inhibits Angiogenesis by Binding to SHC1 and Suppressing Its Phosphorylation

The mitogen-inducible gene 6 (MIG6) is an adaptor protein widely expressed in vascular endothelial cells. However, it remains unknown thus far whether it plays a role in angiogenesis. Here, using comprehensive in vitro and in vivo model systems, we unveil a potent anti-angiogenic effect of MIG6 in r...

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Detalles Bibliográficos
Autores principales: Liu, Lixian, Xing, Liying, Chen, Rongyuan, Zhang, Jianing, Huang, Yuye, Huang, Lijuan, Xie, Bingbing, Ren, Xiangrong, Wang, Shasha, Kuang, Haiqing, Lin, Xianchai, Kumar, Anil, Kim, Jong Kyong, Lee, Chunsik, Li, Xuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937727/
https://www.ncbi.nlm.nih.gov/pubmed/33693003
http://dx.doi.org/10.3389/fcell.2021.634242

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