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Application of Random Mutagenesis and Synthetic FadR Promoter for de novo Production of ω-Hydroxy Fatty Acid in Yarrowia lipolytica
As a means to develop oleaginous biorefinery, Yarrowia lipolytica was utilized to produce ω-hydroxy palmitic acid from glucose using evolutionary metabolic engineering and synthetic FadR promoters for cytochrome P450 (CYP) expression. First, a base strain was constructed to produce free fatty acids...
Autores principales: | Park, Beom Gi, Kim, Junyeob, Kim, Eun-Jung, Kim, Yechan, Kim, Joonwon, Kim, Jin Young, Kim, Byung-Gee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937803/ https://www.ncbi.nlm.nih.gov/pubmed/33692989 http://dx.doi.org/10.3389/fbioe.2021.624838 |
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