Cargando…

Mechanism of Lipid Accumulation through PAR2 Signaling in Diabetic Male Mice

BACKGROUND: Protease-activated protein-2 (PAR2) has been reported to regulate hepatic insulin resistance condition in type 2 diabetes mice. However, the mechanism of lipid metabolism through PAR2 in obesity mice have not yet been examined. In liver, Forkhead box O1 (FoxO1) activity induces peroxisom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Dae Hyun, Kim, Ye Ra, Bang, EunJin, Ha, Sugyeong, Noh, Sang Gyun, Kim, Byeong Moo, Jeong, Seong Ho, Jung, Hee Jin, Lee, Ji Young, Chung, Hae Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Endocrine Society 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937841/ https://www.ncbi.nlm.nih.gov/pubmed/33677938 http://dx.doi.org/10.3803/EnM.2020.850

Ejemplares similares

Modulation of senoinflammation by calorie restriction based on biochemical and Omics big data analysis
por: Bang, EunJin, et al.
Publicado: (2019)

Organ-differential Roles of Akt/FoxOs Axis as a Key Metabolic Modulator during Aging
por: Kim, Dae Hyun, et al.
Publicado: (2021)

β-Hydroxybutyrate Suppresses Lipid Accumulation in Aged Liver through GPR109A-mediated Signaling
por: Lee, A Kyoung, et al.
Publicado: (2020)

Evaluation of the Novel Synthetic Tyrosinase Inhibitor (Z)-3-(3-bromo-4-hydroxybenzylidene)thiochroman-4-one (MHY1498) In Vitro and In Silico
por: Bang, EunJin, et al.
Publicado: (2018)

PAR2 Deficiency Induces Mitochondrial ROS Generation and Dysfunctions, Leading to the Inhibition of Adipocyte Differentiation
por: Park, Yeo Jin, et al.
Publicado: (2021)

Anti-Aging Effects of Calorie Restriction (CR) and CR Mimetics Based on the Senoinflammation Concept
por: Kim, Dae Hyun, et al.
Publicado: (2020)

Interaction between CHOP and FoxO6 promotes hepatic lipid accumulation
por: Kim, Dae Hyun, et al.
Publicado: (2020)

Protease-activated receptor 2 induces ROS-mediated inflammation through Akt-mediated NF-κB and FoxO6 modulation during skin photoaging
por: Bang, EunJin, et al.
Publicado: (2021)

PPARα Agonist, MHY3200, Alleviates Renal Inflammation during Aging via Regulating ROS/Akt/FoxO1 Signaling
por: Kim, Min Jo, et al.
Publicado: (2021)

Impacts of Calorie Restriction and Intermittent Fasting on Health and Diseases: Current Trends
por: Chung, Hae Young, et al.
Publicado: (2020)

Anti-inflammatory action of β-hydroxybutyrate via modulation of PGC-1α and FoxO1, mimicking calorie restriction
por: Kim, Dae Hyun, et al.
Publicado: (2019)

Small RNAs induce the activation of the pro‐inflammatory TLR7 signaling pathway in aged rat kidney
por: Lee, Eun Kyeong, et al.
Publicado: (2017)

Altered FoxO1 and PPARγ interaction in age-related ER stress-induced hepatic steatosis
por: Kim, Dae Hyun, et al.
Publicado: (2019)

Regulation of Circadian Genes Nr1d1 and Nr1d2 in Sex-Different Manners during Liver Aging
por: Noh, Sang Gyun, et al.
Publicado: (2022)

Adiponectin is associated with inflammaging and age-related salivary gland lipid accumulation
por: Kim, Ji Won, et al.
Publicado: (2023)

Combination of Medicinal Herbs KIOM-79 Reduces Advanced Glycation End Product Accumulation and the Expression of Inflammatory Factors in the Aorta of Zucker Diabetic Fatty Rats
por: Sohn, Eunjin, et al.
Publicado: (2011)

Effect of Enzymatic Treatment of Chrysanthemum Indicum Linné Extracts on Lipid Accumulation and Adipogenesis in High-Fat-Diet-Induced Obese Male Mice
por: Lee, Ji-Hyun, et al.
Publicado: (2019)

Parkin deficiency prevents chronic ethanol-induced hepatic lipid accumulation through β-catenin accumulation
por: Lee, Dong Hun, et al.
Publicado: (2019)

GD3 Accumulation in Cell Surface Lipid Rafts Prior to Mitochondrial Targeting Contributes to Amyloid-β-induced Apoptosis
por: Kim, Jong-Kook, et al.
Publicado: (2010)

Polygonum cuspidatum inhibits pancreatic lipase activity and adipogenesis via attenuation of lipid accumulation
por: Kim, Young Sook, et al.
Publicado: (2013)

PPAR Pan Agonist MHY2013 Alleviates Renal Fibrosis in a Mouse Model by Reducing Fibroblast Activation and Epithelial Inflammation
por: Son, Minjung, et al.
Publicado: (2023)

TLR7 activation by miR-21 promotes renal fibrosis by activating the pro-inflammatory signaling pathway in tubule epithelial cells
por: Kim, Jeongwon, et al.
Publicado: (2023)

Red Pepper Seeds Inhibit Hepatic Lipid Accumulation by Inducing Autophagy via AMPK Activation
por: Lee, Young-Hyun, et al.
Publicado: (2022)

Branched-chain amino acids sustain pancreatic cancer growth by regulating lipid metabolism
por: Lee, Ji Hyeon, et al.
Publicado: (2019)

β-Asarone Alleviates High-Glucose-Induced Oxidative Damage via Inhibition of ROS Generation and Inactivation of the NF-κB/NLRP3 Inflammasome Pathway in Human Retinal Pigment Epithelial Cells
por: Park, Cheol, et al.
Publicado: (2023)

Frontline nurses' burnout and its associated factors during the COVID-19 pandemic in South Korea
por: Noh, Eun-Young, et al.
Publicado: (2022)

Cheong-sang-bang-pung-san alleviated hepatic lipid accumulation by regulating lipid metabolism in vitro and in vivo
por: Kang, Yun-Mi, et al.
Publicado: (2023)

Soyasapogenol C from Fermented Soybean (Glycine Max) Acting as a Novel AMPK/PPARα Dual Activator Ameliorates Hepatic Steatosis: A Novel SANDA Methodology
por: Arulkumar, Radha, et al.
Publicado: (2022)

Metformin reduces saturated fatty acid-induced lipid accumulation and inflammatory response by restoration of autophagic flux in endothelial cells
por: Kim, Hae-Suk, et al.
Publicado: (2020)

IDH2 gene deficiency accelerates unilateral ureteral obstruction-induced kidney inflammation through oxidative stress and activation of macrophages
por: Kim, Jee In, et al.
Publicado: (2021)

One-year prevalence and clinical characteristics in chronic dizziness: The 2019–2020 Korean National Health and Nutrition Examination Survey
por: Kim, Eun Ji, et al.
Publicado: (2022)

Adiponectin Signaling Regulates Lipid Production in Human Sebocytes
por: Jung, Yu Ra, et al.
Publicado: (2017)

Evaluation of Salivary Biomarkers of Periodontal Disease Based on Smoking Status: A Systematic Review
por: Noh, Jin-won, et al.
Publicado: (2022)

The Potential of Minor Ginsenosides Isolated from the Leaves of Panax ginseng as Inhibitors of Melanogenesis
por: Lee, Dae-Young, et al.
Publicado: (2015)

Atypical Epidemiologic Finding in Association between Depression and Alcohol Use or Smoking in Korean Male: Korean Longitudinal Study of Aging
por: Noh, Jin-Won, et al.
Publicado: (2014)

Suppression of Lipid Accumulation in the Differentiation of 3T3-L1 Preadipocytes and Human Adipose Stem Cells into Adipocytes by TAK-715, a Specific Inhibitor of p38 MAPK
por: Perumal, Nivethasri Lakshmana, et al.
Publicado: (2023)

Influences of socioeconomic factors on childhood and adolescent overweight by gender in Korea: cross-sectional analysis of nationally representative sample
por: Noh, Jin-Won, et al.
Publicado: (2014)

The involvement of serum exosomal miR-500-3p and miR-770-3p in aging: modulation by calorie restriction
por: Lee, Eun Kyeong, et al.
Publicado: (2017)

Role of Synbiotics Containing d-Allulose in the Alteration of Body Fat and Hepatic Lipids in Diet-Induced Obese Mice
por: Choi, Bo-Ra, et al.
Publicado: (2018)

Spermidine Attenuates High Glucose-Induced Oxidative Damage in Retinal Pigment Epithelial Cells by Inhibiting Production of ROS and NF-κB/NLRP3 Inflammasome Pathway
por: Bang, EunJin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_i7f8rtl7b0hekuupqvbndkhlu5