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Dyslipidemia among allergic rhinitis patients: Frequency and risk factors
BACKGROUND: Although cumulative data strongly suggest an association between dyslipidemia and allergic disorders, especially asthma, evidence regarding allergic rhinitis (AR) is lacking. We aimed to assess frequency and associated risk factors of dyslipidemia among patients with AR. METHODS: The cur...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
World Allergy Organization
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937983/ https://www.ncbi.nlm.nih.gov/pubmed/33747342 http://dx.doi.org/10.1016/j.waojou.2021.100523 |
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author | Sheha, Dina S. El-Korashi, Lobna A. AbdAllah, Amany M. El-Begermy, Marwa M. Elmahdi, Amira R. |
author_facet | Sheha, Dina S. El-Korashi, Lobna A. AbdAllah, Amany M. El-Begermy, Marwa M. Elmahdi, Amira R. |
author_sort | Sheha, Dina S. |
collection | PubMed |
description | BACKGROUND: Although cumulative data strongly suggest an association between dyslipidemia and allergic disorders, especially asthma, evidence regarding allergic rhinitis (AR) is lacking. We aimed to assess frequency and associated risk factors of dyslipidemia among patients with AR. METHODS: The current study is a cross-sectional study that recruited 150 AR patients by systematic randomization. Blood samples for serum lipid profile, total immunoglobulin E (IgE) and serum interleukin-17A (IL-17A) were withdrawn from all patients. RESULTS: Dyslipidemia was prevalent in 84 AR patients (56%). Higher levels of total IgE, IL17-A, and sensitization to hay dust and mixed mites significantly increased the risk of dyslipidemia among AR patients by 1.004, 1.062, 4.057 and 3.652 respectively (P < 0.05). CONCLUSION: High serum total IgE level, high serum IL-17A level, and sensitization to hay dust and mixed mites are independent risk factors for dyslipidemia among AR patients. |
format | Online Article Text |
id | pubmed-7937983 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | World Allergy Organization |
record_format | MEDLINE/PubMed |
spelling | pubmed-79379832021-03-18 Dyslipidemia among allergic rhinitis patients: Frequency and risk factors Sheha, Dina S. El-Korashi, Lobna A. AbdAllah, Amany M. El-Begermy, Marwa M. Elmahdi, Amira R. World Allergy Organ J Article BACKGROUND: Although cumulative data strongly suggest an association between dyslipidemia and allergic disorders, especially asthma, evidence regarding allergic rhinitis (AR) is lacking. We aimed to assess frequency and associated risk factors of dyslipidemia among patients with AR. METHODS: The current study is a cross-sectional study that recruited 150 AR patients by systematic randomization. Blood samples for serum lipid profile, total immunoglobulin E (IgE) and serum interleukin-17A (IL-17A) were withdrawn from all patients. RESULTS: Dyslipidemia was prevalent in 84 AR patients (56%). Higher levels of total IgE, IL17-A, and sensitization to hay dust and mixed mites significantly increased the risk of dyslipidemia among AR patients by 1.004, 1.062, 4.057 and 3.652 respectively (P < 0.05). CONCLUSION: High serum total IgE level, high serum IL-17A level, and sensitization to hay dust and mixed mites are independent risk factors for dyslipidemia among AR patients. World Allergy Organization 2021-03-05 /pmc/articles/PMC7937983/ /pubmed/33747342 http://dx.doi.org/10.1016/j.waojou.2021.100523 Text en © 2021 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Sheha, Dina S. El-Korashi, Lobna A. AbdAllah, Amany M. El-Begermy, Marwa M. Elmahdi, Amira R. Dyslipidemia among allergic rhinitis patients: Frequency and risk factors |
title | Dyslipidemia among allergic rhinitis patients: Frequency and risk factors |
title_full | Dyslipidemia among allergic rhinitis patients: Frequency and risk factors |
title_fullStr | Dyslipidemia among allergic rhinitis patients: Frequency and risk factors |
title_full_unstemmed | Dyslipidemia among allergic rhinitis patients: Frequency and risk factors |
title_short | Dyslipidemia among allergic rhinitis patients: Frequency and risk factors |
title_sort | dyslipidemia among allergic rhinitis patients: frequency and risk factors |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937983/ https://www.ncbi.nlm.nih.gov/pubmed/33747342 http://dx.doi.org/10.1016/j.waojou.2021.100523 |
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