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In vitro complex formation of human PYRIN domain-only protein 3 prevented by self-oligomerization of ASC PYD domain
The formation of inflammasome complexes contributes inactivation of inflammatory caspases viz caspase 1, which is generally considered essential for the innate response. Three proteins constituted this inflammasome complex, such as Nod-like receptors (NLRP or AIM2), ASC possessing caspase-recruiting...
Autores principales: | Ahmed Bhat, Eijaz, Sajjad, Nasreena, Ahmad Tantray, Javeed, Hor, Yan-Yan, Rather, Irfan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938106/ https://www.ncbi.nlm.nih.gov/pubmed/33732046 http://dx.doi.org/10.1016/j.sjbs.2020.12.049 |
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