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Self-Assembled DNA Nanostructure as a Carrier for Targeted siRNA Delivery in Glioma Cells

INTRODUCTION: RNA interference is a promising therapy in glioma treatment. However, the application of RNA interference has been limited in glioma therapy by RNA instability and the lack of tumor targeting. Here, we report a novel DNA tetrahedron, which can effectively deliver small interfering RNA...

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Detalles Bibliográficos
Autores principales: Zhou, Yanghao, Yang, Qiang, Wang, Feng, Zhou, Zunjie, Xu, Jing, Cheng, Si, Cheng, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938230/
https://www.ncbi.nlm.nih.gov/pubmed/33692623
http://dx.doi.org/10.2147/IJN.S295598

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