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Low incidence of venous thrombosis but high incidence of arterial thrombotic complications among critically ill COVID-19 patients in Singapore

BACKGROUND: Arterial and venous thrombosis are reported to be common in critically ill COVID-19 patients. METHOD AND RESULTS: This is a national multicenter retrospective observational study involving all consecutive adult COVID-19 patients who required intensive care units (ICU) admission between 2...

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Autores principales: Tan, Chuen Wen, Fan, Bingwen Eugene, Teo, Winnie Z. Y., Tung, Moon Ley, Shafi, Humaira, Christopher, Dheepa, Zheng, Shuwei, Peh, Wee Ming, Chan, Stephrene Seok Wei, Chong, Vanessa Cui Lian, Gallardo, Christian Aledia, Chang, Cheng Chieh Ray, Ling, Li Min, Tan, Jing Yuan, Lee, Ken Cheah Hooi, Phua, Ghee Chee, Cherng, Benjamin Pei Zhi, Low, Jenny Guek Hong, Ho, Vui Kian, Prasad, Vishnu, Wong, Lester Jung Long, Lim, Cheryl Xiu Qi, Chee, Yen Lin, Ong, Kiat Hoe, Lee, Lai Heng, Ng, Heng Joo, Yap, Eng Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938262/
https://www.ncbi.nlm.nih.gov/pubmed/33685477
http://dx.doi.org/10.1186/s12959-021-00268-9
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author Tan, Chuen Wen
Fan, Bingwen Eugene
Teo, Winnie Z. Y.
Tung, Moon Ley
Shafi, Humaira
Christopher, Dheepa
Zheng, Shuwei
Peh, Wee Ming
Chan, Stephrene Seok Wei
Chong, Vanessa Cui Lian
Gallardo, Christian Aledia
Chang, Cheng Chieh Ray
Ling, Li Min
Tan, Jing Yuan
Lee, Ken Cheah Hooi
Phua, Ghee Chee
Cherng, Benjamin Pei Zhi
Low, Jenny Guek Hong
Ho, Vui Kian
Prasad, Vishnu
Wong, Lester Jung Long
Lim, Cheryl Xiu Qi
Chee, Yen Lin
Ong, Kiat Hoe
Lee, Lai Heng
Ng, Heng Joo
Yap, Eng Soo
author_facet Tan, Chuen Wen
Fan, Bingwen Eugene
Teo, Winnie Z. Y.
Tung, Moon Ley
Shafi, Humaira
Christopher, Dheepa
Zheng, Shuwei
Peh, Wee Ming
Chan, Stephrene Seok Wei
Chong, Vanessa Cui Lian
Gallardo, Christian Aledia
Chang, Cheng Chieh Ray
Ling, Li Min
Tan, Jing Yuan
Lee, Ken Cheah Hooi
Phua, Ghee Chee
Cherng, Benjamin Pei Zhi
Low, Jenny Guek Hong
Ho, Vui Kian
Prasad, Vishnu
Wong, Lester Jung Long
Lim, Cheryl Xiu Qi
Chee, Yen Lin
Ong, Kiat Hoe
Lee, Lai Heng
Ng, Heng Joo
Yap, Eng Soo
author_sort Tan, Chuen Wen
collection PubMed
description BACKGROUND: Arterial and venous thrombosis are reported to be common in critically ill COVID-19 patients. METHOD AND RESULTS: This is a national multicenter retrospective observational study involving all consecutive adult COVID-19 patients who required intensive care units (ICU) admission between 23 January 2020 and 30 April 2020 in Singapore. One hundred eleven patients were included and the venous and arterial thrombotic rates in ICU were 1.8% (n = 2) and 9.9% (n = 11), respectively. Major bleeding rate was 14.8% (n = 16). CONCLUSIONS: Critically ill COVID-19 patients in Singapore have lower venous thromboembolism but higher arterial thrombosis rates and bleeding manifestations than other reported cohorts.
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spelling pubmed-79382622021-03-08 Low incidence of venous thrombosis but high incidence of arterial thrombotic complications among critically ill COVID-19 patients in Singapore Tan, Chuen Wen Fan, Bingwen Eugene Teo, Winnie Z. Y. Tung, Moon Ley Shafi, Humaira Christopher, Dheepa Zheng, Shuwei Peh, Wee Ming Chan, Stephrene Seok Wei Chong, Vanessa Cui Lian Gallardo, Christian Aledia Chang, Cheng Chieh Ray Ling, Li Min Tan, Jing Yuan Lee, Ken Cheah Hooi Phua, Ghee Chee Cherng, Benjamin Pei Zhi Low, Jenny Guek Hong Ho, Vui Kian Prasad, Vishnu Wong, Lester Jung Long Lim, Cheryl Xiu Qi Chee, Yen Lin Ong, Kiat Hoe Lee, Lai Heng Ng, Heng Joo Yap, Eng Soo Thromb J Research BACKGROUND: Arterial and venous thrombosis are reported to be common in critically ill COVID-19 patients. METHOD AND RESULTS: This is a national multicenter retrospective observational study involving all consecutive adult COVID-19 patients who required intensive care units (ICU) admission between 23 January 2020 and 30 April 2020 in Singapore. One hundred eleven patients were included and the venous and arterial thrombotic rates in ICU were 1.8% (n = 2) and 9.9% (n = 11), respectively. Major bleeding rate was 14.8% (n = 16). CONCLUSIONS: Critically ill COVID-19 patients in Singapore have lower venous thromboembolism but higher arterial thrombosis rates and bleeding manifestations than other reported cohorts. BioMed Central 2021-03-08 /pmc/articles/PMC7938262/ /pubmed/33685477 http://dx.doi.org/10.1186/s12959-021-00268-9 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Tan, Chuen Wen
Fan, Bingwen Eugene
Teo, Winnie Z. Y.
Tung, Moon Ley
Shafi, Humaira
Christopher, Dheepa
Zheng, Shuwei
Peh, Wee Ming
Chan, Stephrene Seok Wei
Chong, Vanessa Cui Lian
Gallardo, Christian Aledia
Chang, Cheng Chieh Ray
Ling, Li Min
Tan, Jing Yuan
Lee, Ken Cheah Hooi
Phua, Ghee Chee
Cherng, Benjamin Pei Zhi
Low, Jenny Guek Hong
Ho, Vui Kian
Prasad, Vishnu
Wong, Lester Jung Long
Lim, Cheryl Xiu Qi
Chee, Yen Lin
Ong, Kiat Hoe
Lee, Lai Heng
Ng, Heng Joo
Yap, Eng Soo
Low incidence of venous thrombosis but high incidence of arterial thrombotic complications among critically ill COVID-19 patients in Singapore
title Low incidence of venous thrombosis but high incidence of arterial thrombotic complications among critically ill COVID-19 patients in Singapore
title_full Low incidence of venous thrombosis but high incidence of arterial thrombotic complications among critically ill COVID-19 patients in Singapore
title_fullStr Low incidence of venous thrombosis but high incidence of arterial thrombotic complications among critically ill COVID-19 patients in Singapore
title_full_unstemmed Low incidence of venous thrombosis but high incidence of arterial thrombotic complications among critically ill COVID-19 patients in Singapore
title_short Low incidence of venous thrombosis but high incidence of arterial thrombotic complications among critically ill COVID-19 patients in Singapore
title_sort low incidence of venous thrombosis but high incidence of arterial thrombotic complications among critically ill covid-19 patients in singapore
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938262/
https://www.ncbi.nlm.nih.gov/pubmed/33685477
http://dx.doi.org/10.1186/s12959-021-00268-9
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