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Cell-Free DNA: Hope and Potential Application in Cancer

Cell-free DNA (cfDNA) is easily accessible in peripheral blood and can be used as biomarkers for cancer diagnostics, prognostics, and therapeutics. The applications of cfDNA in various areas of cancer management are attracting attention. In this review article, we discuss the potential relevance of...

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Autores principales: Yan, Yan-yan, Guo, Qiao-ru, Wang, Feng-hua, Adhikari, Rameshwar, Zhu, Zhuang-yan, Zhang, Hai-yan, Zhou, Wen-min, Yu, Hua, Li, Jing-quan, Zhang, Jian-ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938321/
https://www.ncbi.nlm.nih.gov/pubmed/33693004
http://dx.doi.org/10.3389/fcell.2021.639233
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author Yan, Yan-yan
Guo, Qiao-ru
Wang, Feng-hua
Adhikari, Rameshwar
Zhu, Zhuang-yan
Zhang, Hai-yan
Zhou, Wen-min
Yu, Hua
Li, Jing-quan
Zhang, Jian-ye
author_facet Yan, Yan-yan
Guo, Qiao-ru
Wang, Feng-hua
Adhikari, Rameshwar
Zhu, Zhuang-yan
Zhang, Hai-yan
Zhou, Wen-min
Yu, Hua
Li, Jing-quan
Zhang, Jian-ye
author_sort Yan, Yan-yan
collection PubMed
description Cell-free DNA (cfDNA) is easily accessible in peripheral blood and can be used as biomarkers for cancer diagnostics, prognostics, and therapeutics. The applications of cfDNA in various areas of cancer management are attracting attention. In this review article, we discuss the potential relevance of using cfDNA analysis in clinical oncology, particularly in cancer screening, early diagnosis, therapeutic evaluation, monitoring disease progression; and determining disease prognosis.
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spelling pubmed-79383212021-03-09 Cell-Free DNA: Hope and Potential Application in Cancer Yan, Yan-yan Guo, Qiao-ru Wang, Feng-hua Adhikari, Rameshwar Zhu, Zhuang-yan Zhang, Hai-yan Zhou, Wen-min Yu, Hua Li, Jing-quan Zhang, Jian-ye Front Cell Dev Biol Cell and Developmental Biology Cell-free DNA (cfDNA) is easily accessible in peripheral blood and can be used as biomarkers for cancer diagnostics, prognostics, and therapeutics. The applications of cfDNA in various areas of cancer management are attracting attention. In this review article, we discuss the potential relevance of using cfDNA analysis in clinical oncology, particularly in cancer screening, early diagnosis, therapeutic evaluation, monitoring disease progression; and determining disease prognosis. Frontiers Media S.A. 2021-02-22 /pmc/articles/PMC7938321/ /pubmed/33693004 http://dx.doi.org/10.3389/fcell.2021.639233 Text en Copyright © 2021 Yan, Guo, Wang, Adhikari, Zhu, Zhang, Zhou, Yu, Li and Zhang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cell and Developmental Biology
Yan, Yan-yan
Guo, Qiao-ru
Wang, Feng-hua
Adhikari, Rameshwar
Zhu, Zhuang-yan
Zhang, Hai-yan
Zhou, Wen-min
Yu, Hua
Li, Jing-quan
Zhang, Jian-ye
Cell-Free DNA: Hope and Potential Application in Cancer
title Cell-Free DNA: Hope and Potential Application in Cancer
title_full Cell-Free DNA: Hope and Potential Application in Cancer
title_fullStr Cell-Free DNA: Hope and Potential Application in Cancer
title_full_unstemmed Cell-Free DNA: Hope and Potential Application in Cancer
title_short Cell-Free DNA: Hope and Potential Application in Cancer
title_sort cell-free dna: hope and potential application in cancer
topic Cell and Developmental Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938321/
https://www.ncbi.nlm.nih.gov/pubmed/33693004
http://dx.doi.org/10.3389/fcell.2021.639233
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