Multimeric antibodies from antigen-specific human IgM(+) memory B cells restrict Plasmodium parasites

Multimeric immunoglobulin-like molecules arose early in vertebrate evolution, yet the unique contributions of multimeric IgM antibodies to infection control are not well understood. This is partially due to the difficulty of distinguishing low-affinity IgM, secreted rapidly by plasmablasts, from hig...

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Detalles Bibliográficos
Autores principales: Thouvenel, Christopher D., Fontana, Mary F., Netland, Jason, Krishnamurty, Akshay T., Takehara, Kennidy K., Chen, Yu, Singh, Suruchi, Miura, Kazutoyo, Keitany, Gladys J., Lynch, Eric M., Portugal, Silvia, Miranda, Marcos C., King, Neil P., Kollman, Justin M., Crompton, Peter D., Long, Carole A., Pancera, Marie, Rawlings, David J., Pepper, Marion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938364/
https://www.ncbi.nlm.nih.gov/pubmed/33661302
http://dx.doi.org/10.1084/jem.20200942

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