A Network Pharmacology Study of the Molecular Mechanisms of Hypericum japonicum in the Treatment of Cholestatic Hepatitis with Validation in an Alpha-Naphthylisothiocyanate (ANIT) Hepatotoxicity Rat Model

BACKGROUND: This network pharmacology study aimed to identify the active compounds and molecular mechanisms involved in the effects of Hypericum japonicum on cholestatic hepatitis. We validated the findings in an alpha-naphthylisothiocyanate (ANIT) rat model of hepatotoxicity. MATERIAL/METHODS: The...

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Detalles Bibliográficos
Autores principales: Feng, Sen Ling, Zhang, Jing, Jin, Hongliu, Zhu, Wen Ting, Yuan, Zhongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938440/
https://www.ncbi.nlm.nih.gov/pubmed/33657087
http://dx.doi.org/10.12659/MSM.928402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938440/
https://www.ncbi.nlm.nih.gov/pubmed/33657087
http://dx.doi.org/10.12659/MSM.928402

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