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Methylation status of vault RNA 2-1 promoter is a predictor of glycemic response to glucagon-like peptide-1 analog therapy in type 2 diabetes mellitus

INTRODUCTION: Therapeutic efficiency of glucagon-like peptide-1 (GLP-1) analog is about 50%–70% in type 2 diabetes mellitus (T2DM). Discovery of potential genetic biomarkers for prediction of treatment efficiency of GLP-1 analog before therapy is still necessary. We assess whether DNA methylation wa...

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Detalles Bibliográficos
Autores principales:	Lin, Chia-Hung, Lee, Yun-Shien, Huang, Yu-Yao, Tsai, Chi-Neu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7938984/ https://www.ncbi.nlm.nih.gov/pubmed/33674278 http://dx.doi.org/10.1136/bmjdrc-2020-001416

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