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Differential and longitudinal immune gene patterns associated with reprogrammed microenvironment and viral mimicry in response to neoadjuvant radiotherapy in rectal cancer

BACKGROUND: Rectal cancers show a highly varied response to neoadjuvant radiotherapy/chemoradiation (RT/CRT) and the impact of the tumor immune microenvironment on this response is poorly understood. Current clinical tumor regression grading systems attempt to measure radiotherapy response but are s...

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Detalles Bibliográficos
Autores principales:	Wilkins, Anna, Fontana, Elisa, Nyamundanda, Gift, Ragulan, Chanthirika, Patil, Yatish, Mansfield, David, Kingston, Jennifer, Errington-Mais, Fiona, Bottomley, Daniel, von Loga, Katharina, Bye, Hannah, Carter, Paul, Tinkler-Hundal, Emma, Noshirwani, Arish, Downs, Jessica, Dillon, Magnus, Demaria, Sandra, Sebag-Montefiore, David, Harrington, Kevin, West, Nick, Melcher, Alan, Sadanandam, Anguraj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Immunotherapy Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939016/ https://www.ncbi.nlm.nih.gov/pubmed/33678606 http://dx.doi.org/10.1136/jitc-2020-001717

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