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Early sedation with dexmedetomidine in ventilated critically ill patients and heterogeneity of treatment effect in the SPICE III randomised controlled trial
PURPOSE: To quantify potential heterogeneity of treatment effect (HTE), of early sedation with dexmedetomidine (DEX) compared with usual care, and identify patients who have a high probability of lower or higher 90-day mortality according to age, and other identified clusters. METHODS: Bayesian anal...
Autores principales: | Shehabi, Yahya, Serpa Neto, Ary, Howe, Belinda D., Bellomo, Rinaldo, Arabi, Yaseen M., Bailey, Michael, Bass, Frances E., Kadiman, Suhaini Bin, McArthur, Colin J., Reade, Michael C., Seppelt, Ian M., Takala, Jukka, Wise, Matt P., Webb, Steve A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939103/ https://www.ncbi.nlm.nih.gov/pubmed/33686482 http://dx.doi.org/10.1007/s00134-021-06356-8 |
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