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SPARC enables genetic manipulation of precise proportions of cells.

Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific fractions of a genetically defined cell type is challenging. We developed Sparse Predictive Activity through Recom...

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Detalles Bibliográficos
Autores principales: Isaacman-Beck, Jesse, Paik, Kristine C., Wienecke, Carl F. R., Yang, Helen H., Fisher, Yvette E., Wang, Irving E., Ishida, Itzel G., Maimon, Gaby, Wilson, Rachel I., Clandinin, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939234/
https://www.ncbi.nlm.nih.gov/pubmed/32690967
http://dx.doi.org/10.1038/s41593-020-0668-9