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MMP activation–associated aminopeptidase N reveals a bivalent 14-3-3 binding motif

Aminopeptidase N (APN, CD13) is a transmembrane ectopeptidase involved in many crucial cellular functions. Besides its role as a peptidase, APN also mediates signal transduction and is involved in the activation of matrix metalloproteinases (MMPs). MMPs function in tissue remodeling within the extra...

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Detalles Bibliográficos
Autores principales:	Kiehstaller, Sebastian, Ottmann, Christian, Hennig, Sven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939381/ https://www.ncbi.nlm.nih.gov/pubmed/33109610 http://dx.doi.org/10.1074/jbc.RA120.014708

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