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Therapeutic targeting of pancreatic cancer stem cells by dexamethasone modulation of the MKP-1–JNK axis

Postoperative recurrence from microscopic residual disease must be prevented to cure intractable cancers, including pancreatic cancer. Key to this goal is the elimination of cancer stem cells (CSCs) endowed with tumor-initiating capacity and drug resistance. However, current therapeutic strategies c...

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Detalles Bibliográficos
Autores principales:	Suzuki, Shuhei, Okada, Masashi, Sanomachi, Tomomi, Togashi, Keita, Seino, Shizuka, Sato, Atsushi, Yamamoto, Masahiro, Kitanaka, Chifumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Molecular Bases of Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939393/ https://www.ncbi.nlm.nih.gov/pubmed/33115754 http://dx.doi.org/10.1074/jbc.RA120.015223

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