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Nitro-fatty acids as activators of hSIRT6 deacetylase activity

Sirtuin 6, SIRT6, is critical for both glucose and lipid homeostasis and is involved in maintaining genomic stability under conditions of oxidative DNA damage such as those observed in age-related diseases. There is an intense search for modulators of SIRT6 activity, however, not many specific activ...

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Detalles Bibliográficos
Autores principales:	Carreño, Mara, Bresque, Mariana, Machado, Matías R., Santos, Leonardo, Durán, Rosario, Vitturi, Darío A., Escande, Carlos, Denicola, Ana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Enzymology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939442/ https://www.ncbi.nlm.nih.gov/pubmed/33122195 http://dx.doi.org/10.1074/jbc.RA120.014883

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