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Molecular characterization of the RNA-protein complex directing −2/−1 programmed ribosomal frameshifting during arterivirus replicase expression

Programmed ribosomal frameshifting (PRF) is a mechanism used by arteriviruses like porcine reproductive and respiratory syndrome virus (PRRSV) to generate multiple proteins from overlapping reading frames within its RNA genome. PRRSV employs −1 PRF directed by RNA secondary and tertiary structures w...

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Detalles Bibliográficos
Autores principales: Patel, Ankoor, Treffers, Emmely E., Meier, Markus, Patel, Trushar R., Stetefeld, Jörg, Snijder, Eric J., Mark, Brian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939443/
https://www.ncbi.nlm.nih.gov/pubmed/33127640
http://dx.doi.org/10.1074/jbc.RA120.016105