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Molecular architecture and domain arrangement of the placental malaria protein VAR2CSA suggests a model for carbohydrate binding
VAR2CSA is the placental-malaria–specific member of the antigenically variant Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family. It is expressed on the surface of Plasmodium falciparum-infected host red blood cells and binds to specific chondroitin-4-sulfate chains of the placenta...
Autores principales: | Bewley, Maria C., Gautam, Lovely, Jagadeeshaprasad, Mashanipalya G., Gowda, D. Channe, Flanagan, John M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939466/ https://www.ncbi.nlm.nih.gov/pubmed/33122198 http://dx.doi.org/10.1074/jbc.RA120.014676 |
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