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Determinants of replication protein A subunit interactions revealed using a phosphomimetic peptide

Replication protein A (RPA) is a eukaryotic ssDNA-binding protein and contains three subunits: RPA70, RPA32, and RPA14. Phosphorylation of the N-terminal region of the RPA32 subunit plays an essential role in DNA metabolism in processes such as replication and damage response. Phosphorylated RPA32 (...

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Detalles Bibliográficos
Autores principales: Lee, Sungjin, Heo, Jeongbeen, Park, Chin-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939470/
https://www.ncbi.nlm.nih.gov/pubmed/33127641
http://dx.doi.org/10.1074/jbc.RA120.016457

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