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Determinants of replication protein A subunit interactions revealed using a phosphomimetic peptide
Replication protein A (RPA) is a eukaryotic ssDNA-binding protein and contains three subunits: RPA70, RPA32, and RPA14. Phosphorylation of the N-terminal region of the RPA32 subunit plays an essential role in DNA metabolism in processes such as replication and damage response. Phosphorylated RPA32 (...
Autores principales: | Lee, Sungjin, Heo, Jeongbeen, Park, Chin-Ju |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939470/ https://www.ncbi.nlm.nih.gov/pubmed/33127641 http://dx.doi.org/10.1074/jbc.RA120.016457 |
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