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FUS contributes to mTOR-dependent inhibition of translation
The amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)–linked RNA-binding protein called FUS (fused in sarcoma) has been implicated in several aspects of RNA regulation, including mRNA translation. The mechanism by which FUS affects the translation of polyribosomes has not been es...
Autores principales: | Sévigny, Myriam, Bourdeau Julien, Isabelle, Venkatasubramani, Janani Priya, Hui, Jeremy B., Dutchak, Paul A., Sephton, Chantelle F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939483/ https://www.ncbi.nlm.nih.gov/pubmed/33082139 http://dx.doi.org/10.1074/jbc.RA120.013801 |
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