Cargando…

Obesity and Disease Severity Among Patients With COVID-19

Background Obesity can be associated with one or more co-morbidities that worsen the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Studies demonstrated that severe forms of coronavirus disease (COVID-19) have occurred in elderly patients and patients with co-morbidities suc...

Descripción completa

Detalles Bibliográficos
Autores principales: Motaib, Imane, Zbiri, Saad, Elamari, Saloua, Dini, Nezha, Chadli, Asma, El Kettani, Chafik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939537/
https://www.ncbi.nlm.nih.gov/pubmed/33717716
http://dx.doi.org/10.7759/cureus.13165
_version_ 1783661770944020480
author Motaib, Imane
Zbiri, Saad
Elamari, Saloua
Dini, Nezha
Chadli, Asma
El Kettani, Chafik
author_facet Motaib, Imane
Zbiri, Saad
Elamari, Saloua
Dini, Nezha
Chadli, Asma
El Kettani, Chafik
author_sort Motaib, Imane
collection PubMed
description Background Obesity can be associated with one or more co-morbidities that worsen the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Studies demonstrated that severe forms of coronavirus disease (COVID-19) have occurred in elderly patients and patients with co-morbidities such as diabetes, hypertension, and cardiovascular diseases. Objective This study investigated the impact of obesity on COVID-19 severity, irrespective of other individual factors. Methods This retrospective observational study included all adult patients with confirmed COVID-19 infection, who were admitted to Sheikh Khalifa Ibn Zaid International University Hospital between March 20 and May 10, 2020. First, we compared patients with and those without obesity in terms of demographic characteristics, co-morbidities, clinical symptoms, and outcomes. Further, using logistic regression models, we analyzed the association between obesity and intensive care unit (ICU) admission. Also, we examined whether the association between obesity and ICU admission was also consistent among overweight patients. Results The study population included 107 patients with confirmed COVID-19 infection. Obese patients have been admitted in ICU more than patients without obesity (P-value = 0.035). While adjusting for other risk factors for ICU admission, we found that obesity was an independent risk factor for ICU admission (OR = 5.04, 95% CI (1.14-22.37)). When we examined the association of both obesity and overweight with ICU admission, we found that only obesity was significantly associated with ICU admission (OR = 9.11, 95% CI (1.49-55.84)). Conclusion Our study found that obesity was strongly associated with severity of COVID-19. The risk of ICU admission is greater in the presence of obesity. Physicians should be awarded to the need of specific and early management of obese patients with COVID-19 disease.
format Online
Article
Text
id pubmed-7939537
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-79395372021-03-11 Obesity and Disease Severity Among Patients With COVID-19 Motaib, Imane Zbiri, Saad Elamari, Saloua Dini, Nezha Chadli, Asma El Kettani, Chafik Cureus Endocrinology/Diabetes/Metabolism Background Obesity can be associated with one or more co-morbidities that worsen the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Studies demonstrated that severe forms of coronavirus disease (COVID-19) have occurred in elderly patients and patients with co-morbidities such as diabetes, hypertension, and cardiovascular diseases. Objective This study investigated the impact of obesity on COVID-19 severity, irrespective of other individual factors. Methods This retrospective observational study included all adult patients with confirmed COVID-19 infection, who were admitted to Sheikh Khalifa Ibn Zaid International University Hospital between March 20 and May 10, 2020. First, we compared patients with and those without obesity in terms of demographic characteristics, co-morbidities, clinical symptoms, and outcomes. Further, using logistic regression models, we analyzed the association between obesity and intensive care unit (ICU) admission. Also, we examined whether the association between obesity and ICU admission was also consistent among overweight patients. Results The study population included 107 patients with confirmed COVID-19 infection. Obese patients have been admitted in ICU more than patients without obesity (P-value = 0.035). While adjusting for other risk factors for ICU admission, we found that obesity was an independent risk factor for ICU admission (OR = 5.04, 95% CI (1.14-22.37)). When we examined the association of both obesity and overweight with ICU admission, we found that only obesity was significantly associated with ICU admission (OR = 9.11, 95% CI (1.49-55.84)). Conclusion Our study found that obesity was strongly associated with severity of COVID-19. The risk of ICU admission is greater in the presence of obesity. Physicians should be awarded to the need of specific and early management of obese patients with COVID-19 disease. Cureus 2021-02-05 /pmc/articles/PMC7939537/ /pubmed/33717716 http://dx.doi.org/10.7759/cureus.13165 Text en Copyright © 2021, Motaib et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Motaib, Imane
Zbiri, Saad
Elamari, Saloua
Dini, Nezha
Chadli, Asma
El Kettani, Chafik
Obesity and Disease Severity Among Patients With COVID-19
title Obesity and Disease Severity Among Patients With COVID-19
title_full Obesity and Disease Severity Among Patients With COVID-19
title_fullStr Obesity and Disease Severity Among Patients With COVID-19
title_full_unstemmed Obesity and Disease Severity Among Patients With COVID-19
title_short Obesity and Disease Severity Among Patients With COVID-19
title_sort obesity and disease severity among patients with covid-19
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939537/
https://www.ncbi.nlm.nih.gov/pubmed/33717716
http://dx.doi.org/10.7759/cureus.13165
work_keys_str_mv AT motaibimane obesityanddiseaseseverityamongpatientswithcovid19
AT zbirisaad obesityanddiseaseseverityamongpatientswithcovid19
AT elamarisaloua obesityanddiseaseseverityamongpatientswithcovid19
AT dininezha obesityanddiseaseseverityamongpatientswithcovid19
AT chadliasma obesityanddiseaseseverityamongpatientswithcovid19
AT elkettanichafik obesityanddiseaseseverityamongpatientswithcovid19