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HP1β carries an acidic linker domain and requires H3K9me3 for phase separation

Liquid-liquid phase separation (LLPS) mediated formation of membraneless organelles has been proposed to coordinate biological processes in space and time. Previously, the formation of phase-separated droplets was described as a unique property of HP1α. Here, we demonstrate that the positive net cha...

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Detalles Bibliográficos
Autores principales: Qin, Weihua, Stengl, Andreas, Ugur, Enes, Leidescher, Susanne, Ryan, Joel, Cardoso, M. Cristina, Leonhardt, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939559/
https://www.ncbi.nlm.nih.gov/pubmed/33660589
http://dx.doi.org/10.1080/19491034.2021.1889858