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Identification of guanine nucleotide exchange factors that increase Cdc42 activity in primary human endothelial cells
The Rho GTPase family is involved in actin dynamics and regulates the barrier function of the endothelium. One of the main barrier-promoting Rho GTPases is Cdc42, also known as cell division control protein 42 homolog. Currently, regulation of Cdc42-based signalling networks in endothelial cells (EC...
Autores principales: | Reinhard, Nathalie R., Van Der Niet, Sanne, Chertkova, Anna, Postma, Marten, Hordijk, Peter L., Gadella Jr., Theodorus W.J., Goedhart, Joachim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939571/ https://www.ncbi.nlm.nih.gov/pubmed/31469028 http://dx.doi.org/10.1080/21541248.2019.1658509 |
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