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Prognosis of Japanese Patients With Coronary Artery Disease Who Underwent Implantable Cardioverter Defibrillator Implantation ― The JID-CAD Study ―

Background: There has been no large multicenter clinical trial on the prognosis of implantable cardioverter defibrillator (ICD) or cardiac resynchronization therapy with a defibrillator (CRT-D) in Japanese patients with coronary artery disease (CAD). The aim of the present study was to compare diffe...

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Autores principales: Kabutoya, Tomoyuki, Mitsuhashi, Takeshi, Shimizu, Akihiko, Nitta, Takashi, Mitamura, Hideo, Kurita, Takashi, Abe, Haruhiko, Nakazato, Yuji, Sumitomo, Naokata, Kadota, Kazushige, Kimura, Kazuo, Okumura, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Circulation Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939950/
https://www.ncbi.nlm.nih.gov/pubmed/33693292
http://dx.doi.org/10.1253/circrep.CR-20-0122
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author Kabutoya, Tomoyuki
Mitsuhashi, Takeshi
Shimizu, Akihiko
Nitta, Takashi
Mitamura, Hideo
Kurita, Takashi
Abe, Haruhiko
Nakazato, Yuji
Sumitomo, Naokata
Kadota, Kazushige
Kimura, Kazuo
Okumura, Ken
author_facet Kabutoya, Tomoyuki
Mitsuhashi, Takeshi
Shimizu, Akihiko
Nitta, Takashi
Mitamura, Hideo
Kurita, Takashi
Abe, Haruhiko
Nakazato, Yuji
Sumitomo, Naokata
Kadota, Kazushige
Kimura, Kazuo
Okumura, Ken
author_sort Kabutoya, Tomoyuki
collection PubMed
description Background: There has been no large multicenter clinical trial on the prognosis of implantable cardioverter defibrillator (ICD) or cardiac resynchronization therapy with a defibrillator (CRT-D) in Japanese patients with coronary artery disease (CAD). The aim of the present study was to compare differences in the prognoses of Japanese patients with CAD between primary and secondary prevention, and to identify potential predictors of prognosis. Methods and Results: We investigated 392 CAD patients (median age 69 years, 90% male) treated with ICD/CRT-D enrolled in the Japan Implantable Devices in CAD (JID-CAD) Registry. The primary endpoint was all-cause death, and the secondary endpoint was appropriate ICD therapies. Endpoints were assessed by dividing patients into primary prevention (n=165) and secondary prevention (n=227) groups. The mean (±SD) follow-up period was 2.1±0.9 years. The primary endpoint was similar in the 2 groups (P=0.350). Conclusions: The mortality rate in Japanese patients with CAD who underwent ICD/CRT-D implantation as primary prevention was not lower than that of patients who underwent ICD/CRT-D implantation as secondary prevention, despite the lower cardiac function in the patients undergoing ICD/CRT-D implantation as primary prevention.
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spelling pubmed-79399502021-03-09 Prognosis of Japanese Patients With Coronary Artery Disease Who Underwent Implantable Cardioverter Defibrillator Implantation ― The JID-CAD Study ― Kabutoya, Tomoyuki Mitsuhashi, Takeshi Shimizu, Akihiko Nitta, Takashi Mitamura, Hideo Kurita, Takashi Abe, Haruhiko Nakazato, Yuji Sumitomo, Naokata Kadota, Kazushige Kimura, Kazuo Okumura, Ken Circ Rep Original article Background: There has been no large multicenter clinical trial on the prognosis of implantable cardioverter defibrillator (ICD) or cardiac resynchronization therapy with a defibrillator (CRT-D) in Japanese patients with coronary artery disease (CAD). The aim of the present study was to compare differences in the prognoses of Japanese patients with CAD between primary and secondary prevention, and to identify potential predictors of prognosis. Methods and Results: We investigated 392 CAD patients (median age 69 years, 90% male) treated with ICD/CRT-D enrolled in the Japan Implantable Devices in CAD (JID-CAD) Registry. The primary endpoint was all-cause death, and the secondary endpoint was appropriate ICD therapies. Endpoints were assessed by dividing patients into primary prevention (n=165) and secondary prevention (n=227) groups. The mean (±SD) follow-up period was 2.1±0.9 years. The primary endpoint was similar in the 2 groups (P=0.350). Conclusions: The mortality rate in Japanese patients with CAD who underwent ICD/CRT-D implantation as primary prevention was not lower than that of patients who underwent ICD/CRT-D implantation as secondary prevention, despite the lower cardiac function in the patients undergoing ICD/CRT-D implantation as primary prevention. The Japanese Circulation Society 2021-01-14 /pmc/articles/PMC7939950/ /pubmed/33693292 http://dx.doi.org/10.1253/circrep.CR-20-0122 Text en Copyright © 2021, THE JAPANESE CIRCULATION SOCIETY This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license.https://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Original article
Kabutoya, Tomoyuki
Mitsuhashi, Takeshi
Shimizu, Akihiko
Nitta, Takashi
Mitamura, Hideo
Kurita, Takashi
Abe, Haruhiko
Nakazato, Yuji
Sumitomo, Naokata
Kadota, Kazushige
Kimura, Kazuo
Okumura, Ken
Prognosis of Japanese Patients With Coronary Artery Disease Who Underwent Implantable Cardioverter Defibrillator Implantation ― The JID-CAD Study ―
title Prognosis of Japanese Patients With Coronary Artery Disease Who Underwent Implantable Cardioverter Defibrillator Implantation ― The JID-CAD Study ―
title_full Prognosis of Japanese Patients With Coronary Artery Disease Who Underwent Implantable Cardioverter Defibrillator Implantation ― The JID-CAD Study ―
title_fullStr Prognosis of Japanese Patients With Coronary Artery Disease Who Underwent Implantable Cardioverter Defibrillator Implantation ― The JID-CAD Study ―
title_full_unstemmed Prognosis of Japanese Patients With Coronary Artery Disease Who Underwent Implantable Cardioverter Defibrillator Implantation ― The JID-CAD Study ―
title_short Prognosis of Japanese Patients With Coronary Artery Disease Who Underwent Implantable Cardioverter Defibrillator Implantation ― The JID-CAD Study ―
title_sort prognosis of japanese patients with coronary artery disease who underwent implantable cardioverter defibrillator implantation ― the jid-cad study ―
topic Original article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939950/
https://www.ncbi.nlm.nih.gov/pubmed/33693292
http://dx.doi.org/10.1253/circrep.CR-20-0122
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