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A theoretical study on the effects of interdomain flexibility on drug encounter rate for coronavirus nucleocapsid-type proteins
To study the effects of the interdomain flexibility on the encounter rate of nucleocapsid-type protein with drug molecules, where two domains (NTD) are connected by a flexible linker and each NTD has a drug binding site, two-dimensional random walk simulation was carried out as a function of the int...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier B.V.
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939999/ https://www.ncbi.nlm.nih.gov/pubmed/33730680 http://dx.doi.org/10.1016/j.bpc.2021.106574 |