Variable Gut Function Recovery After Right vs. Left Colectomy May Be Due to Rectosigmoid Hyperactivity

It is established that gut function recovers slower after right vs. left colectomies with higher rates of prolonged post-operative ileus (PPOI), but the reason is unclear. Development of PPOI is multifactorial. A recent manometry study in right colectomy patients showed that the distal colon becomes...

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Detalles Bibliográficos
Autores principales: Seo, Sean Ho Beom, Bissett, Ian, O’Grady, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940204/
https://www.ncbi.nlm.nih.gov/pubmed/33708140
http://dx.doi.org/10.3389/fphys.2021.635167
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author Seo, Sean Ho Beom
Bissett, Ian
O’Grady, Gregory
author_facet Seo, Sean Ho Beom
Bissett, Ian
O’Grady, Gregory
author_sort Seo, Sean Ho Beom
collection PubMed
description It is established that gut function recovers slower after right vs. left colectomies with higher rates of prolonged post-operative ileus (PPOI), but the reason is unclear. Development of PPOI is multifactorial. A recent manometry study in right colectomy patients showed that the distal colon becomes hyperactive after surgery with predominantly cyclic motor patterns (CMPs). In this perspective, we evaluate the hypothesis that the slower gut recovery after right hemicolectomy could be induced by a functional obstruction due to hyperactive CMPs.
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spelling pubmed-79402042021-03-10 Variable Gut Function Recovery After Right vs. Left Colectomy May Be Due to Rectosigmoid Hyperactivity Seo, Sean Ho Beom Bissett, Ian O’Grady, Gregory Front Physiol Physiology It is established that gut function recovers slower after right vs. left colectomies with higher rates of prolonged post-operative ileus (PPOI), but the reason is unclear. Development of PPOI is multifactorial. A recent manometry study in right colectomy patients showed that the distal colon becomes hyperactive after surgery with predominantly cyclic motor patterns (CMPs). In this perspective, we evaluate the hypothesis that the slower gut recovery after right hemicolectomy could be induced by a functional obstruction due to hyperactive CMPs. Frontiers Media S.A. 2021-02-23 /pmc/articles/PMC7940204/ /pubmed/33708140 http://dx.doi.org/10.3389/fphys.2021.635167 Text en Copyright © 2021 Seo, Bissett and O’Grady. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Seo, Sean Ho Beom
Bissett, Ian
O’Grady, Gregory
Variable Gut Function Recovery After Right vs. Left Colectomy May Be Due to Rectosigmoid Hyperactivity
title Variable Gut Function Recovery After Right vs. Left Colectomy May Be Due to Rectosigmoid Hyperactivity
title_full Variable Gut Function Recovery After Right vs. Left Colectomy May Be Due to Rectosigmoid Hyperactivity
title_fullStr Variable Gut Function Recovery After Right vs. Left Colectomy May Be Due to Rectosigmoid Hyperactivity
title_full_unstemmed Variable Gut Function Recovery After Right vs. Left Colectomy May Be Due to Rectosigmoid Hyperactivity
title_short Variable Gut Function Recovery After Right vs. Left Colectomy May Be Due to Rectosigmoid Hyperactivity
title_sort variable gut function recovery after right vs. left colectomy may be due to rectosigmoid hyperactivity
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940204/
https://www.ncbi.nlm.nih.gov/pubmed/33708140
http://dx.doi.org/10.3389/fphys.2021.635167
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