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Suppression of optineurin impairs the progression of hepatocellular carcinoma through regulating mitophagy
Autophagy removes damaged organelles to inhibit malignant transformation during tumor initiation. Once a cancer matures, it uses the autophagic pathway as an energy source. Optineurin (OPTN) is an autophagy adaptor protein that recruits microtubule‐associated protein 1 light chain 3, an autophagosom...
Autores principales: | Inokuchi, Shoichi, Yoshizumi, Tomoharu, Toshima, Takeo, Itoh, Shinji, Yugawa, Kyohei, Harada, Noboru, Mori, Hiroyuki, Fukuhara, Takasuke, Matsuura, Yoshiharu, Mori, Masaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940236/ https://www.ncbi.nlm.nih.gov/pubmed/33600074 http://dx.doi.org/10.1002/cam4.3519 |
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