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Myofibrillar Structural Variability Underlies Contractile Function in Stem Cell-Derived Cardiomyocytes
Disease modeling and pharmaceutical testing using cardiomyocytes derived from induced pluripotent stem cells (iPSC-CMs) requires accurate assessment of contractile function. Micropatterning iPSC-CMs on elastic substrates controls cell shape and alignment to enable contractile studies, but determinan...
Autores principales: | Ufford, Kathryn, Friedline, Sabrina, Tong, Zhaowen, Tang, Vi T., Dobbs, Amani S., Tsan, Yao-Chang, Bielas, Stephanie L., Liu, Allen P., Helms, Adam S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940249/ https://www.ncbi.nlm.nih.gov/pubmed/33577793 http://dx.doi.org/10.1016/j.stemcr.2021.01.007 |
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