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Myofibrillar Structural Variability Underlies Contractile Function in Stem Cell-Derived Cardiomyocytes

Disease modeling and pharmaceutical testing using cardiomyocytes derived from induced pluripotent stem cells (iPSC-CMs) requires accurate assessment of contractile function. Micropatterning iPSC-CMs on elastic substrates controls cell shape and alignment to enable contractile studies, but determinan...

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Detalles Bibliográficos
Autores principales: Ufford, Kathryn, Friedline, Sabrina, Tong, Zhaowen, Tang, Vi T., Dobbs, Amani S., Tsan, Yao-Chang, Bielas, Stephanie L., Liu, Allen P., Helms, Adam S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940249/
https://www.ncbi.nlm.nih.gov/pubmed/33577793
http://dx.doi.org/10.1016/j.stemcr.2021.01.007

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