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Rbbp4 Suppresses Premature Differentiation of Embryonic Stem Cells

Polycomb group (PcG) proteins exist in distinct multi-protein complexes and play a central role in silencing developmental genes, yet the underlying mechanisms remain elusive. Here, we show that deficiency of retinoblastoma binding protein 4 (RBBP4), a component of the Polycomb repressive complex 2...

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Detalles Bibliográficos
Autores principales: Huang, Yikai, Su, Ting, Wang, Congcong, Dong, Lixia, Liu, Shuang, Zhu, Yaru, Hao, Kunying, Xia, Yin, Jiang, Qing, Qin, Jinzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940252/
https://www.ncbi.nlm.nih.gov/pubmed/33606987
http://dx.doi.org/10.1016/j.stemcr.2021.01.009