Development of the Nude Rabbit Model

Loss-of-function mutations in the forkhead box N1 (FOXN1) gene lead to nude severe combined immunodeficiency, a rare inherited syndrome characterized by athymia, severe T cell immunodeficiency, congenital alopecia, and nail dystrophy. We recently produced FOXN1 mutant nude rabbits (NuRabbits) by usi...

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Detalles Bibliográficos
Autores principales: Song, Jun, Hoenerhoff, Mark, Yang, Dongshan, Yang, Ying, Deng, Cheng, Wen, Luan, Ma, Linyuan, Pallas, Brooke, Zhao, Changzhi, Koike, Yui, Koike, Tomonari, Lester, Patrick, Yang, Bo, Zhang, Jifeng, Chen, Y. Eugene, Xu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940256/
https://www.ncbi.nlm.nih.gov/pubmed/33606990
http://dx.doi.org/10.1016/j.stemcr.2021.01.010

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