Cargando…

Sodium–glucose cotransporter 2 inhibitors reduce myocardial infarct size in preclinical animal models of myocardial ischaemia–reperfusion injury: a meta-analysis

AIMS/HYPOTHESIS: Large cardiovascular outcome trials demonstrated that the cardioprotective effects of sodium–glucose cotransporter 2 (SGLT2) inhibitors might reach beyond glucose-lowering action. In this meta-analysis, we sought to evaluate the potential infarct size-modulating effect of SGLT2 inhi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sayour, Alex Ali, Celeng, Csilla, Oláh, Attila, Ruppert, Mihály, Merkely, Béla, Radovits, Tamás
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940278/ https://www.ncbi.nlm.nih.gov/pubmed/33483761 http://dx.doi.org/10.1007/s00125-020-05359-2

Ejemplares similares

Characterization of left ventricular myocardial sodium-glucose cotransporter 1 expression in patients with end-stage heart failure
por: Sayour, Alex Ali, et al.
Publicado: (2020)

Effects of SGLT2 Inhibitors beyond Glycemic Control—Focus on Myocardial SGLT1
por: Sayour, Alex Ali, et al.
Publicado: (2021)

Acute canagliflozin treatment protects against in vivo myocardial ischemia–reperfusion injury in non-diabetic male rats and enhances endothelium-dependent vasorelaxation
por: Sayour, Alex Ali, et al.
Publicado: (2019)

Left Ventricular SGLT1 Protein Expression Correlates with the Extent of Myocardial Nitro-Oxidative Stress in Rats with Pressure and Volume Overload-Induced Heart Failure
por: Sayour, Alex Ali, et al.
Publicado: (2021)

Myocardial work index: a marker of left ventricular contractility in pressure‐ or volume overload‐induced heart failure
por: Lakatos, Bálint Károly, et al.
Publicado: (2021)

Sex-related differences of early cardiac functional and proteomic alterations in a rat model of myocardial ischemia
por: Barta, Bálint András, et al.
Publicado: (2021)

Novel insights into the athlete’s heart: is myocardial work the new champion of systolic function?
por: Tokodi, Márton, et al.
Publicado: (2021)

Inflammasome activation in end‐stage heart failure‐associated atrial fibrillation
por: Kugler, Szilvia, et al.
Publicado: (2022)

Pressure overload-induced systolic heart failure is associated with characteristic myocardial microRNA expression signature and post-transcriptional gene regulation in male rats
por: Ruppert, Mihály, et al.
Publicado: (2023)

Balanced Intense Exercise Training Induces Atrial Oxidative Stress Counterbalanced by the Antioxidant System and Atrial Hypertrophy That Is Not Associated with Pathological Remodeling or Arrhythmogenicity
por: Oláh, Attila, et al.
Publicado: (2021)

Comparison of the Reverse-Remodeling Effect of Pharmacological Soluble Guanylate Cyclase Activation With Pressure Unloading in Pathological Myocardial Left Ventricular Hypertrophy
por: Ruppert, Mihály, et al.
Publicado: (2019)

Sex Differences in Morphological and Functional Aspects of Exercise-Induced Cardiac Hypertrophy in a Rat Model
por: Oláh, Attila, et al.
Publicado: (2019)

Pharmacological preconditioning with gemfibrozil preserves cardiac function after heart transplantation
por: Benke, Kálmán, et al.
Publicado: (2017)

Survival of Myocardial Infarction Patients with Diabetes Mellitus at the Invasive Era (Results from the Városmajor Myocardial Infarction Registry)
por: Skoda, Réka, et al.
Publicado: (2023)

Cinaciguat prevents the development of pathologic hypertrophy in a rat model of left ventricular pressure overload
por: Németh, Balázs Tamás, et al.
Publicado: (2016)

Mouse models of myocardial infarction: comparing permanent ligation and ischaemia-reperfusion
por: De Villiers, Carla, et al.
Publicado: (2020)

Stimulation of soluble guanylate cyclase improves donor organ function in rat heart transplantation
por: Benke, Kálmán, et al.
Publicado: (2020)

IL-1β neutralization prevents diastolic dysfunction development, but lacks hepatoprotective effect in an aged mouse model of NASH
por: Kucsera, Dániel, et al.
Publicado: (2023)

The Sodium-Glucose Cotransporter-2 Inhibitor Canagliflozin Alleviates Endothelial Dysfunction Following In Vitro Vascular Ischemia/Reperfusion Injury in Rats
por: Korkmaz-Icöz, Sevil, et al.
Publicado: (2021)

Comparison of speckle-tracking echocardiography with invasive hemodynamics for the detection of characteristic cardiac dysfunction in type-1 and type-2 diabetic rat models
por: Mátyás, Csaba, et al.
Publicado: (2018)

Protocol: does sodium nitrite administration reduce ischaemia-reperfusion injury in patients presenting with acute ST segment elevation myocardial infarction? Nitrites in acute myocardial infarction (NIAMI)
por: Siddiqi, Nishat, et al.
Publicado: (2013)

The cardioprotective potential of valsartan in myocardial ischaemia reperfusion injury
por: Hadi, Najah R., et al.
Publicado: (2015)

Lower myocardial stress perfusion in infarct-adjacent than in remote myocardium four months after revascularized myocardial infarction
por: Goetschalckx, Kaatje, et al.
Publicado: (2015)

The differential effects of FTY720 on functional recovery and infarct size following myocardial ischaemia/ reperfusion
por: van Vuuren, Derick, et al.
Publicado: (2016)

The soluble guanylate cyclase activator cinaciguat prevents cardiac dysfunction in a rat model of type-1 diabetes mellitus
por: Mátyás, Csaba, et al.
Publicado: (2015)

An Altered Pattern of Myocardial Histopathological and Molecular Changes Underlies the Different Characteristics of Type-1 and Type-2 Diabetic Cardiac Dysfunction
por: Radovits, Tamás, et al.
Publicado: (2015)

Conditioned Medium from Mesenchymal Stem Cells Alleviates Endothelial Dysfunction of Vascular Grafts Submitted to Ischemia/Reperfusion Injury in 15-Month-Old Rats
por: Korkmaz-Icöz, Sevil, et al.
Publicado: (2021)

Lower myocardial perfusion in borderzones in the area at risk than out of the area at risk in acute myocardial infarction
por: Goetschalckx, Kaatje, et al.
Publicado: (2015)

Custodiol-N, the novel cardioplegic solution reduces ischemia/reperfusion injury after cardiopulmonary bypass
por: Veres, Gábor, et al.
Publicado: (2015)

Inhibition of adenosine kinase attenuates myocardial ischaemia/reperfusion injury
por: Wang, Wenjun, et al.
Publicado: (2021)

Extracellular histones are a target in myocardial ischaemia–reperfusion injury
por: Shah, Mohammed, et al.
Publicado: (2021)

Alterations in mitochondrial protein glycosylation in myocardial ischaemia reperfusion injury
por: Feng, Xinyu, et al.
Publicado: (2023)

Evaluation of muscle-specific and metabolism regulating microRNAs in a chronic swimming rat model
por: Gaál, Zsuzsanna, et al.
Publicado: (2021)

Mesenchymal stem cell-derived conditioned medium protects vascular grafts of brain-dead rats against in vitro ischemia/reperfusion injury
por: Korkmaz-Icöz, Sevil, et al.
Publicado: (2021)

Reduction in the incidence of myocardial infarction with sodium–glucose linked cotransporter-2 inhibitors: evident and plausible
por: Gilbert, Richard E., et al.
Publicado: (2019)

Prevention of the development of heart failure with preserved ejection fraction by the phosphodiesterase‐5A inhibitor vardenafil in rats with type 2 diabetes
por: Mátyás, Csaba, et al.
Publicado: (2016)

Influence of dextran-70 on systemic inflammatory response and myocardial ischaemia-reperfusion following cardiac operations
por: Gombocz, Károly, et al.
Publicado: (2007)

Changes and Relationship of PAF and TNF in Rats with Myocardial Ischaemia and Reperfusion Injury
por: Han, Ya-Ling, et al.
Publicado: (1994)

Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury
por: Barry, Seán P., et al.
Publicado: (2013)

Melatonin has profound effects on mitochondrial dynamics in myocardial ischaemia/reperfusion
por: Dube, K., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_207hp7jurk7ljc36feiuqt8qti