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Hypoxia-Mediated Complement 1q Binding Protein Regulates Metastasis and Chemoresistance in Triple-Negative Breast Cancer and Modulates the PKC-NF-κB-VCAM-1 Signaling Pathway

OBJECTIVES: Complement 1q binding protein (C1QBP/HABP1/p32/gC1qR) has been found to be overexpressed in triple-negative breast cancer (TNBC). However, the underlying mechanisms of high C1QBP expression and its role in TNBC remain largely unclear. Hypoxia is a tumor-associated microenvironment that p...

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Detalles Bibliográficos
Autores principales:	Wu, Hao, Chu, Yijun, Sun, Shanshan, Li, Guozheng, Xu, Shouping, Zhang, Xianyu, Jiang, Yongdong, Gao, Song, Wang, Qin, Zhang, Jian, Pang, Da
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940382/ https://www.ncbi.nlm.nih.gov/pubmed/33708767 http://dx.doi.org/10.3389/fcell.2021.607142

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