In cis TP53 and RAD51C pathogenic variants may predispose to sebaceous gland carcinomas

Pathogenic variants in TP53 have been classically thought to cause Li-Fraumeni syndrome (LFS), a cancer predisposition with high risks for various childhood- and adult-onset malignancies. However, increased genetic testing has lately revealed, that pathogenic variant carriers exhibit a broader range...

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Detalles Bibliográficos
Autores principales: Le Duc, Diana, Hentschel, Julia, Neuser, Sonja, Stiller, Mathias, Meier, Carolin, Jäger, Elisabeth, Abou Jamra, Rami, Platzer, Konrad, Monecke, Astrid, Ziemer, Mirjana, Markovic, Aleksander, Bläker, Hendrik, Lemke, Johannes R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940394/
https://www.ncbi.nlm.nih.gov/pubmed/33319852
http://dx.doi.org/10.1038/s41431-020-00781-x

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