Coculture with hiPS-derived intestinal cells enhanced human hepatocyte functions in a pneumatic-pressure-driven two-organ microphysiological system

Examining intestine–liver interactions is important for achieving the desired physiological drug absorption and metabolism response in in vitro drug tests. Multi-organ microphysiological systems (MPSs) constitute promising tools for evaluating inter-organ interactions in vitro. For coculture on MPSs...

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Detalles Bibliográficos
Autores principales: Shinohara, Marie, Arakawa, Hiroshi, Oda, Yuuichi, Shiraki, Nobuaki, Sugiura, Shinji, Nishiuchi, Takumi, Satoh, Taku, Iino, Keita, Leo, Sylvia, Kato, Yusuke, Araya, Karin, Kawanishi, Takumi, Nakatsuji, Tomoki, Mitsuta, Manami, Inamura, Kosuke, Goto, Tomomi, Shinha, Kenta, Nihei, Wataru, Komori, Kikuo, Nishikawa, Masaki, Kume, Shoen, Kato, Yukio, Kanamori, Toshiyuki, Sakai, Yasuyuki, Kimura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940409/
https://www.ncbi.nlm.nih.gov/pubmed/33686099
http://dx.doi.org/10.1038/s41598-021-84861-y

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