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Prefrontal dopamine D1 receptor manipulation influences anxiety behavior and induces neuroinflammation within the hippocampus

BACKGROUND: Prefrontal dopamine D1 receptor (D1R) mediates behavior related to anxiety, reward and memory, and is involved in inflammatory processes, all of which are affected in bipolar disorder. Interleukin-6 (IL-6), a pro-inflammatory cytokine, is increased in patients with bipolar disorder in pl...

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Detalles Bibliográficos
Autores principales: Beyer, Dominik K. E., Mattukat, Annika, Freund, Nadja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940461/
https://www.ncbi.nlm.nih.gov/pubmed/33683478
http://dx.doi.org/10.1186/s40345-020-00212-2