Cargando…
Therapeutic Implications of Targeting Heat Shock Protein 70 by Immunization or Antibodies in Experimental Skin Inflammation
Heat shock proteins (Hsp) are constitutive and stress-induced molecules which have been reported to impact innate and adaptive immune responses. Here, we evaluated the role of Hsp70 as a treatment target in the imiquimod-induced, psoriasis-like skin inflammation mouse model and related in vitro assa...
Autores principales: | Tukaj, Stefan, Mantej, Jagoda, Sobala, Michał, Potrykus, Katarzyna, Tukaj, Zbigniew, Zillikens, Detlef, Ludwig, Ralf J., Bieber, Katja, Kasperkiewicz, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940535/ https://www.ncbi.nlm.nih.gov/pubmed/33708208 http://dx.doi.org/10.3389/fimmu.2021.614320 |
Ejemplares similares
-
Pathological Relevance of Anti-Hsp70 IgG Autoantibodies in Epidermolysis Bullosa Acquisita
por: Tukaj, Stefan, et al.
Publicado: (2022) -
Autologous extracellular Hsp70 exerts a dual role in rheumatoid arthritis
por: Tukaj, Stefan, et al.
Publicado: (2020) -
Inhibitory effects of heat shock protein 90 blockade on proinflammatory human Th1 and Th17 cell subpopulations
por: Tukaj, Stefan, et al.
Publicado: (2014) -
Autoantibodies to heat shock protein 60, 70, and 90 are not altered in the anti-SARS-CoV-2 IgG-seropositive humans without or with mild symptoms
por: Mantej, Jagoda, et al.
Publicado: (2021) -
Targeting heat shock proteins 90 and 70: A promising remedy for both autoimmune bullous diseases and COVID-19
por: Kasperkiewicz, Michael, et al.
Publicado: (2022)