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Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment
Brain metastases are the most common tumor of the brain with a dismal prognosis. A fraction of patients with brain metastasis benefit from treatment with immune checkpoint inhibitors (ICI) and the degree and phenotype of the immune cell infiltration has been used to predict response to ICI. However,...
Autores principales: | Rubio-Perez, Carlota, Planas-Rigol, Ester, Trincado, Juan L., Bonfill-Teixidor, Ester, Arias, Alexandra, Marchese, Domenica, Moutinho, Catia, Serna, Garazi, Pedrosa, Leire, Iurlaro, Raffaella, Martínez-Ricarte, Francisco, Escudero, Laura, Cordero, Esteban, Cicuendez, Marta, Ruiz, Sara, Parra, Genís, Nuciforo, Paolo, Gonzalez, Josep, Pineda, Estela, Sahuquillo, Juan, Tabernero, Josep, Heyn, Holger, Seoane, Joan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940606/ https://www.ncbi.nlm.nih.gov/pubmed/33686071 http://dx.doi.org/10.1038/s41467-021-21789-x |
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