Deep learning-based enhancement of epigenomics data with AtacWorks

ATAC-seq is a widely-applied assay used to measure genome-wide chromatin accessibility; however, its ability to detect active regulatory regions can depend on the depth of sequencing coverage and the signal-to-noise ratio. Here we introduce AtacWorks, a deep learning toolkit to denoise sequencing co...

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Detalles Bibliográficos
Autores principales: Lal, Avantika, Chiang, Zachary D., Yakovenko, Nikolai, Duarte, Fabiana M., Israeli, Johnny, Buenrostro, Jason D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940635/
https://www.ncbi.nlm.nih.gov/pubmed/33686069
http://dx.doi.org/10.1038/s41467-021-21765-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940635/
https://www.ncbi.nlm.nih.gov/pubmed/33686069
http://dx.doi.org/10.1038/s41467-021-21765-5

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