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Treatment of Chronic Venous Ulcers With Heterologous Fibrin Sealant: A Phase I/II Clinical Trial
BACKGROUND: Heterologous fibrin sealant (HFS) consists of a fibrinogen-rich cryoprecipitate extracted from Bubalus bubalis buffalo blood and a thrombin-like enzyme purified from Crotalus durissus terrificus snake venom. This study evaluated the safety and immunogenicity of HFS, estimated the best do...
Autores principales: | Abbade, Luciana P. F., Barraviera, Silvia Regina Catharino Sartori, Silvares, Maria Regina Cavariani, Lima, Ana Beatriz B. de C. O., Haddad, Gabriela R., Gatti, Márcia A. N., Medolago, Natália Bronzatto, Rigotto Carneiro, Márcia Tonin, dos Santos, Lucilene Delazari, Ferreira, Rui Seabra, Barraviera, Benedito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940668/ https://www.ncbi.nlm.nih.gov/pubmed/33708219 http://dx.doi.org/10.3389/fimmu.2021.627541 |
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