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Elevated Brain Glutamate Levels in Bipolar Disorder and Pyruvate Carboxylase-Mediated Anaplerosis

In vivo (1)H magnetic resonance spectroscopy studies have found elevated brain glutamate or glutamate + glutamine levels in bipolar disorder with surprisingly high reproducibility. We propose that the elevated glutamate levels in bipolar disorder can be explained by increased pyruvate carboxylase-me...

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Detalles Bibliográficos
Autores principales: Shen, Jun, Tomar, Jyoti Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940766/
https://www.ncbi.nlm.nih.gov/pubmed/33708149
http://dx.doi.org/10.3389/fpsyt.2021.640977

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