The effects of UCP2 on autophagy through the AMPK signaling pathway in septic cardiomyopathy and the underlying mechanism

BACKGROUND: Mitochondrial dysfunction plays an important role in the development of septic cardiomyopathy. This study aimed to reveal the protective role of uncoupling protein 2 (UCP2) in mitochondria through AMP-activated protein kinase (AMPK) on autophagy during septic cardiomyopathy. METHODS: UCP...

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Detalles Bibliográficos
Autores principales: Mao, Jia-Yu, Su, Long-Xiang, Li, Dong-Kai, Zhang, Hong-Min, Wang, Xiao-Ting, Liu, Da-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940903/
https://www.ncbi.nlm.nih.gov/pubmed/33708886
http://dx.doi.org/10.21037/atm-20-4819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940903/
https://www.ncbi.nlm.nih.gov/pubmed/33708886
http://dx.doi.org/10.21037/atm-20-4819

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