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FEN1 is a prognostic biomarker for ER+ breast cancer and associated with tamoxifen resistance through the ERα/cyclin D1/Rb axis
BACKGROUND: Tamoxifen is an important choice in endocrine therapy for patients with oestrogen receptor-positive (ER+) breast cancer, and disease progression-associated resistance to tamoxifen therapy is still challenging. Flap endonuclease-1 (FEN1) is used as a prognostic biomarker and is considered...
Autores principales: | Xu, Lu, Shen, Ji-Ming, Qu, Jing-Lei, Song, Na, Che, Xiao-Fang, Hou, Ke-Zuo, Shi, Jing, Zhao, Lei, Shi, Sha, Liu, Yun-Peng, Qu, Xiu-Juan, Teng, Yue-E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940940/ https://www.ncbi.nlm.nih.gov/pubmed/33708885 http://dx.doi.org/10.21037/atm-20-3068 |
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